Recombinant human IGF-1

Insulin-like growth factors (IGFs) belong to the insulin gene family and are a mitogenic polypeptide growth factor that stimulates the proliferation and survival of muscle, bone, cartilage and other cells in vitro. Recombinant human insulin-like growth factor 1 (IGF-1) is a biologically active protein for cell culture. It binds to the receptor IGF1R and activates multiple signaling pathways. It can participate in cell proliferation, differentiation, survival, growth, apoptosis and regeneration.

 This product is a lyophilized powder prepared by recombinant Pichia pastoris, further purified by multiple steps, and then freeze-dried.

★ Product features

l   No animal origin: the product is free of animal virus, no pathogenic substances, no external factor pollution, and high safety.

l   High purity: SDS-PAGE purity reached 98%.

l   High biological activity: 2 x 10^5 IU per 1 mg of protein.

l   Use a small amount of protein to achieve the desired experimental results.

l   Quality stability: This product is a lyophilized powder containing bioactive protective agent. It has been mass-produced and the difference between batches is small.

★  Product Properties

Biological activity: The biological activity of IGF-1 was measured by stimulating the human breast cancer cell line MCF-7.

★  Product  Application

     It can be used for cell culture to enhance cell proliferation, cell growth and cell differentiation.

★    Usage method

l      It is recommended to centrifuge the powder immediately before opening the lid to sink the powder to the bottom of the tube, then dissolve it in sterilized deionized water to prepare a storage solution of 100 μg/ml. It can be stored stably for 1 week at 2 °C ~ 8 °C. When diluted to a lower concentration (not less than 10 μg/ml), 0.1% BSA or HSA is required. If it is necessary to extend the storage time, it is recommended to freeze at -70 ° C or -20 ° C. It is not recommended to repeat freezing and thawing.

l      This product is only used for research and should not be used on animals and humans.